Table 1.
# | Parameter | Value |
---|---|---|
1 | Patient mass (kg) | 77.7 |
2 | F01 (mmol/kg▪min) | 0.0097 |
3 | VG (L/kg) | 0.16 |
4 | kG (min-1) | 0.066 |
5 | AG (unitless) | 0.8 |
6 | tmax,G (min) | 40 |
Insulin model constants: Hovorka et al25 and Wilinska et al26 | ||
7 | EGP0 (mmol/kg min) | 0.0161 |
8 | kSQi (dimensionless) | 0.67 |
9 | kSQis (min-1) | 0.0112 |
10 | kSQif (min-1) | 0.0210 |
11 | kei (min-1) | 0.138 |
12 | Vmax,LD (mU/min) | 1.93 |
13 | KM.LD (mU) | 62.6 |
14 | V1 (L/kg) | 0.12 |
15 | kia1 (min-1) | 0.006 |
16 | kia2 (min-1) | 0.06 |
17 | kia3 (min-1) | 0.03 |
18 | SfIT (unitless) | 51.2e-4 |
19 | SfID (unitless) | 8.2e-4 |
20 | SfiE (unitless) | 520e-4 |
Pramlintide model constants: Clodi et al20 | ||
21 | kep (min-1) | 0.1069 |
22 | kp21 (min-1) | 0.1448 |
23 | kp12 (min-1) | 0.1254 |
24 | kp32 (min-1) | 0.0164 |
25 | kp23 (min-1) | 0.0234 |