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Duration curve of suppressive action of 5 nM ZIP on visceral sensitivity in rats of NMS. A–D: the duration curve of the action of 5 nM ZIP on EMG under 20, 40, 60, and 80 mmHg CRD in rats of NMS. The maximal suppression was recorded at 30 min after ZIP administration in rats of NMS; n = 8. *P < 0.05 vs. pre-drug.
