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. 2015 Apr 16;6(1):80. doi: 10.1186/s13287-015-0069-2

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© Maruyama et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of implantation of DFAT cells on proteinuria and renal function in adriamycin-induced nephropathy. Wistar rats were nephrectomized and were injected without adriamycin (Control) or with 4 mg/kg body weight adriamycin through the tail vein without DFAT cells (Saline) or with 10⁶ DFAT cells that were injected through the renal artery (DFAT ia) or tail vein (DFAT iv) in rats after the nephrectomy. Urinary protein excretion (A) and serum levels of BUN (B) and creatinine (Cre) (C) were measured. Data are the mean ± SEM (n = 4). *P <0.05 and **P <0.01 in the indicated columns. BUN, blood urea nitrogen; DFAT, dedifferentiated fat; SEM, standad error of the mean.