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. 2015 Jan 6;8:5. doi: 10.1186/s13071-014-0620-5

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© Abe et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Pathological analysis of brain tissue. Slight to mild lesions including perivascular cuffs were observed in the C57BL/6 mice (A), and slight to moderate lesions including necrotic focus with glial cell infiltration were observed in the CCR5^−/− mice (B). Additionally, the severity of the histopathological lesions was analyzed (C). No significant difference was observed in the pathological score between the two groups (student’s t-test).