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. Author manuscript; available in PMC: 2015 Jun 4.
Published in final edited form as: Anesth Analg. 2012 Mar 30;115(2):450–460. doi: 10.1213/ANE.0b013e3182501a09

Figure 1.

Figure 1

Dose-dependent anti-nociceptive effects of intrathecal clonidine. Mechanical withdrawal thresholds at baseline and 30 minutes following intrathecal (I.T.) injection of saline or clonidine (CL) 1, 3 or 10mg/kg in postnatal day (P) 3, 7 or 21 rat pups are shown. Data points = mean±SEM, n=6–8 per treatment group, *P<0.05 ***P<0.001 one way ANOVA with Dunnett’s comparison to baseline.