Table 1.
Baseline Characteristics of Early-Stage Subjects.
| Variable |
All (N = 360) |
Aripiprazole (N = 237) |
Haloperidol (N = 123) |
P-value a | |||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | ||
| Age (years) | 27.2 | 6.3 | 27.0 | 6.1 | 27.5 | 6.6 | 0.446 |
| Weight (kg) | 71.7 | 15.3 | 71.8 | 15.3 | 71.4 | 15.3 | 0.842 |
| BMI (kg/m2) | 24.1 | 4.7 | 24.2 | 4.8 | 24.0 | 4.5 | 0.772 |
| PANSS total score | 94.3 | 15.4 | 95.2 | 15.1 | 92.5 | 15.8 | 0.117 |
| PANSS negative score | 24.4 | 6.0 | 24.7 | 5.8 | 23.8 | 6.2 | 0.209 |
| PANSS positive score | 24.2 | 4.7 | 24.1 | 4.5 | 24.3 | 5.2 | 0.695 |
| PANSS general score | 45.7 | 8.2 | 46.4 | 8.3 | 44.4 | 8.1 | 0.029 |
| CGI severity score | 4.8 | 0.8 | 4.8 | 0.7 | 4.8 | 0.8 | 0.774 |
| MADRS total score | 13.1 | 8.1 | 13.5 | 8.2 | 12.3 | 7.8 | 0.169 |
| Age at first episode | 24.4 | 6.0 | 24.2 | 5.9 | 24.8 | 6.2 | 0.378 |
| Number of hospitalizations | 2.4 | 2.5 | 2.3 | 2.2 | 2.5 | 3.1 | 0.486 |
| Weeks since relapse began | 3.9 | 4.6 | 4.0 | 5.1 | 3.7 | 3.5 | 0.497 |
| Length of treatment for current relapse (weeks) |
1.4 | 1.3 | 1.4 | 1.4 | 1.4 | 1.2 | 0.963 |
| Mean dose (mg/day) | 28.4 | 3.1 | 8.6 | 1.2 | |||
| N | % | N | % | N | % | |||
|---|---|---|---|---|---|---|---|---|
| Gender | Men | 225 | 62.5 | 149 | 62.9 | 76 | 61.8 | 0.909 |
| Women | 135 | 37.5 | 88 | 37.1 | 47 | 38.2 | ||
| Race | White | 312 | 86.7 | 204 | 86.1 | 108 | 87.8 | 0.185 |
| Black | 33 | 9.2 | 25 | 10.5 | 8 | 6.5 | ||
| Hispanic | 3 | 0.8 | 3 | 1.3 | ||||
| Asian | 3 | 0.8 | 1 | 0.4 | 2 | 1.6 | ||
| Other | 9 | 2.5 | 4 | 1.7 | 5 | 4.1 |
a
t test for numeric variables and Fisher’s exact test for categorical variables.