Table 4.

DNA Ploidy. DI= Diploidy Index, difference in DNA content expressed as the ratio of DNA fluorescence of leukoplakia sample/normal tissue sample

Patient ID	Time of biopsy	% of Diploid Cells	Avg DI of Diploid Cells (Range)	% of Aneuploid Cells	% of Polyploid Cells	Avg DI of Polyploid Cells(Range)
1	Baseline	65	0.84 (0.23-1.1)	35.4	0.8	2.23 (2.0-2.48)
	3 mos.	27	0.86 (0.73-1.1)	73	1	2.31 (2.0-2.43)
2	Baseline	30	0.89 (0.73-1.1)	70	0.1	2.57 (2.0-2.73)
	3 mos.	39	0.93 (0.78-1.1)	61	5.3	2.2 (2.0-2.96)
3	Baseline	14.2	0.98 (0.85-1.1)	86	15.2	2.33 (2.0-4.52)
	3 mos.	25.85	0.94 (0.76-1.1)	73.95	0	2.03 (2.02-2.05)
4	Baseline	33	0.94 (0.74-1.1)	67	1	2.46 (2.0-2.77)
	3 mos.	49	0.99 (0.85-1.1)	51	0.3	2.48 (2.0-3.02)
5	Baseline	41.7	0.96 (0.77-1.1)	58.3	2.2	2.11 (2.0-2.36)
	3 mos.	n/a	n/a	n/a	n/a	n/a
6	Baseline	48.7	0.94 (0.75-1.1)	51.3	n/a	2.31 (2.0-3.91)
	3 mos.	12.78	0.92 (0.73-1.1)	87.2	37	2.35 (2.0-4.33)
7	Baseline		n/a	n/a	n/a	n/a
	3 mos.	39.5	0.93 (0.72-1.1)	60.4	4.2	2.57 (2.02-3.47)
8	Baseline	30	0.93 (0.75-1.1)	70	2.1	2.41 (2.0-2.86)
	3 mos.	44.8	0.94 (0.72-1.1)	55.1	2.2	2.52 (2.03-3.48)
9	Baseline	23	0.89 (0.79-1.1)	76.8	2.4	2.36 (2.0-2.8)
	3 mos.	28.1	0.91 (0.75-1.1)	71.9	2.5	2.21 (2.0-2.38)
10	Baseline	43.8	0.92 (0.75-1.1)	56.2	0	2.42 (2.0-3.24)
	3 mos.	40	0.95 (0.78-1.1)	59	1.6	2.34 (2.0-2.8)
11	Baseline	62	1 (0.63-1.1)	38	1.3	2.29 (2.0-2.35)
	3 mos.	53	0.97 (0.82-1.1)	47	1.2	2.31 (2.0-3.6)