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Vascular responses of mesenteric arteries collected from mice aspirated with either a single (1X) or a repeated exposures (6X) to graded dose of (A) JC or (B) ZH + NiSO4 and subsequently treated with various inhibitors. Differences detected in comparison to the control group and each respected group prior to inhibitor incubation (H2O Ctrl n = 8; ZH n = 6; JC n = 14; ZH + NiSO4 n = 16; n = 5-6/inhibitor groups; *p < 0.05; **p < 0.01; ***p < 0.001). Error bar represents SEM.
