Fig. 2.

a Measurement of the OS+ thicknesses in individual patients (symbols, right) compared to individual controls (blue circles, left). The mean thickness of the controls is represented by the larger red circle. The measured thickness in a patient eye was considered thin if it was less than the minimum thickness in controls (blue dashed line) and/or below the control mean minus two standard deviations (red dashed line). Thinning was observed in some patient eyes (red rectangle). Purple arrows point to thicknesses measured in Patient 1 and green arrows point to thicknesses measured in Patient 2 as described in the text. b Measurement of the REC+ thicknesses in individual patients and individual controls. c Measurement of the INL thicknesses in individual patients and individual controls