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. Author manuscript; available in PMC: 2016 Feb 10.
Published in final edited form as: J Control Release. 2014 Dec 3;199:156–167. doi: 10.1016/j.jconrel.2014.11.016

Table 2.

Representative Lacritin cleavage sequences identified by MALDI-TOF

Fragment *Amino Acid Sequence **Exp.
M.W. [kDa]		 ***Obs.
M.W. [kDa]
1 GEDASSDSTGADPAQEAGTSKPNEEISGPAEPASPPETTTTA
QETSAAAVQGTAKVTSSRQELNPLKSIVEKSILLTEQALAKAG
KGMHGGVPGGKQFIENGSEFAQKLLKKFSLLKPWAGLVPR		 12.84 12.96
2 GEDASSDSTGADPAQEAGTSKPNEEISGPAEPASPPETTTTA
QETSAAAVQGTAKVTSSRQELNPLKSIVEKSILLTEQALAKAG
KGMHGGVPGGKQFIENGSEFAQKLLKKFSLLK		 11.84/
11.97		 12.00
3 GEDASSDSTGADPAQEAGTSKPNEEISGPAEPASPPETTTTA
QETSAAAVQGTAKVTSSRQELNPLKSIVEKSILLTEQALAKAG
KGMHGGVPGGKQFIENGSEFAQKLLKK		 11.25/
11.38
11.35/
11.47/
11.50
4 PNEEISGPAEPASPPETTTTAQETSAAAVQGTAKVTSSRQEL
NPLKSIVEKSILLTEQALAK		 6.42 6.36
*

Underlined sequence: Syndecan-1 binding site

**

Expected M.W. (kDa) for fragments were calculated by DNAStar Lasergene Editseq

***

Observed M.W. (kDa) was measured by MALDI-TOF