Table 2.

AUC of gametocyte density over time, days 1 to 15 after treatment

Other malaria treatment type	Trial	Malaria treatment	Dose PQ mg/kg	AUC with PQ days 1 to 15	AUC without PQ days 1 to 15	% reduction AUC days 1 to 15	log(10)AUC with PQ days 1 to 15	log(10)AUC without PQ days1 to 15	% reduction log(10)AUC days 1 to 15
Non-artemisinin- based	Kolaczinski 2012	a: CQ	0.5	485.26	4266.61	88.6	2.69	3.63	26.0
	Kolaczinski 2012	b: SP	0.5	924.87	5964.77	84.5	2.97	3.78	21.4
Artemisinin- based	Shekalaghe 2007	AS+SP	0.75	40.15	65.06	38.3	1.60	1.81	11.6
	Smithuis 2010	a: AS+AQ	0.75	140.35	428.51	67.3	2.15	2.63	18.4
	Smithuis 2010	b: AL	0.75	196.24	242.86	19.2	2.29	2.39	3.9
	Smithuis 2010	c: AS+MQ fixed	0.75	237.78	510.03	53.4	2.38	2.71	12.2
	Smithuis 2010	d: AS+MQ loose	0.75	183.51	293.28	37.4	2.26	2.47	8.3
	Smithuis 2010	e: DHAP	0.75	295.24	709.60	58.4	2.47	2.85	13.4
	Sutanto 2013	DHAP	0.75	1252.48	2355.84	46.8	3.10	3.37	8.1
	Vasquez 2009	AS+MQ	0.75	500.40	305.67	-63.7	2.70	2.49	-8.6