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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Arch Biochem Biophys. 2015 Jan 3;576:39–48. doi: 10.1016/j.abb.2014.12.018

Figure 1.

Figure 1

High fat diet started in adult female C57BL/6J increases body weight and fat mass and shortens lifespan. Average body weights (A), fat mass (B) and fat-free mass (C) of mice at indicated time points following start of feeding studies at 8 months of age. Bars indicate values ± SEM for n=15 chow (filled) or n=40 high fat (open) fed mice. Letters indicate differences among age-groups of high fat-fed mice as measured by 2 way ANOVA with Bonferroni post-hoc analyses. No differences with age were found among chow-fed mice using these tests. (D) Survival of mice from each group in this study. Arrows indicate time points (4 months and 10 months after initiation of diet studies) at which assays of health parameters were measured.