Figure 3.
Metabolic function is altered by both diet and age. A. Respiratory quotients during light and dark cycles and resting metabolic rate are given for mice 4 months and 10 months after starting high fat diet. Circles represent mean values ± SEM for n=15 chow (filled) or n=40 high fat (open) fed mice. Letters indicate differences among groups as measured by 2 way ANOVA with Bonferroni post-hoc analyses. B. Glucose tolerance tests and insulin levels in chow and high fat fed mice after 10 months of high fat diet. Circles or bars represent mean values ± SEM for n=5 chow (filled) or n=5 high fat (open) fed mice.