Skip to main content
. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Mol Cancer Ther. 2015 Feb 11;14(3):779–787. doi: 10.1158/1535-7163.MCT-14-0228

Figure 5. Notch+ cells possess tumor initiating capacity and show lineage differentiation in mouse xenografts.

Figure 5

(A, C) Notch+ Sum159 and MCF7 cells compared to Notch- cells demonstrated a higher tumor forming capacity in mice xenografts. (B, D) FACS analyses of primary tumor cells showed that Notch+ tumors reconstituted the initial heterogeneity in vivo as evidenced by the presence of both Notch+ and Notch- cells (two independent FACS data presented).