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Tertiary tumor growth and the CSC frequency of Notch+ and Notch− MCF7 breast cancer cell subpopulations in NOD-SCID mice using the serial transplantation assay
| Cell Populations |
Cell number | Tu mors/ Number of Implantations |
CSC frequency |
|---|---|---|---|
| MCF7-Notch+ | 100000 | 3/3 | Notch+ : 16554 |
| MCF7-Notch+ | 60000 | 3/3 | |
| MCF7-Notch+ | 30000 | 3/3 | |
| MCF7-Notch+ | 10000 | 3/3 | |
| MCF7-Notch− | 100000 | 3/3 | Notch−: 62385 |
| MCF7-Notch− | 60000 | 3/3 | |
| MCF7-Notch− | 30000 | 2/3 | |
| MCF7-Notch− | 10000 | 0/3 | |
| p =0.00758 | |||
