Skip to main content
. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Leukemia. 2014 Dec 8;29(6):1350–1359. doi: 10.1038/leu.2014.341

Figure 7. Mechanism of Foxm1 regulation.

Figure 7

(A) IPA predicted interaction among TP53, E2F1 and FOXM1 in TCL1 Tg mice and PTPROt/TCL1 double Tg mice. (B) p53 DNA binding activity in TCL1 Tg and PTPROt/TCL1 double Tg mice. HepG2 (p53WT) and Huh7 (p53mut) were used as positive and negative controls, respectively. (C) Fold change in expression of Ccl3 and Foxm1 as measured by real-time RT-PCR in CD19+ cells isolated from TCL1 Tg mice treated with inhibitors as indicated. (D) Immunoblot analysis of p53 in treated cells. Data is normalized to GAPDH.