Table 1B.
Progression to Stability for Four TCS Measures Among Children Hospitalized with Community-acquired Pneumonia
| <2 years (n=130) | 2-4 years (n=90) | 5-17 years (n=101) | |||||
|---|---|---|---|---|---|---|---|
| TCS Measures | No. (%)1 | Median (IQR) TCS, in hours | No. (%) | Median (IQR) TCS, in hours | No. (%) | Median (IQR) TCS, in hours | p-value2 |
| RR + O2 | 108 (83.1) | 40.5 (20.1, 75.0) | 72 (80.0) | 39.6 (15.6, 79.2) | 69 (68.3) | 30.4 (14.7, 59.2) | .08 |
| RR + O2 + HR | 109 (83.8) | 40.2 (19.5, 73.9) | 73 (81.1) | 35.9 (15.9, 77.6) | 68 (67.3) | 29.8 (17.2, 56.6) | .11 |
| RR + O2 + T | 110 (84.6) | 40.5 (20.7, 70.1) | 77 (85.6) | 39.1 (18.4, 77.6) | 73 (72.3) | 28.2 (14.7, 44.7) | .03 |
| RR + O2 + HR + T | 110 (84.6) | 40.5 (20.7, 70.1) | 72 (80.0) | 39.7 (20.1, 77.5) | 71 (70.3) | 29.2 (18.2, 54) | .05 |
For each measure, time to clinical stability was calculated by subtracting the time and date of the last abnormal value for the included parameters from admission time and date to determine time to stability for each parameter in hours; children stable on admission for all four parameters not included (n=11).
1
Number (%) of children who reached stability more than six hours prior to discharge
2
p-value comparing median TCS by age group, estimated using non-parametric test of trend
abbreviations: TCS, time to clinical stability; IQR, interquartile range; T, temperature; HR, heart rate; RR, respiratory rate; O2, supplemental oxygen