Table 1. Conservation of glycosylation motif in terrestrial vertebrates.

Genus species	Alignment of glycosylation motif context	last aa
Mus musculus	QVLSCVTEGSLESLLNTTYQLRQAARELG-PASRAGSRSLTFEVEGK	192
Bos taurus	QVLRCVTEGSLESLLNTTHWLQTASQALN-PDGQAGSQGLTLQAQGD	192
Ailuropoda melanoleuca	RVLRCVTEGSLESLLNTTHQLHAASRALG-PAGHAGSQGLTLQAQGN	192
Homo sapiens	QVLRCVTEGSLESLLNTTHQLHAASRALG-PTGQAGSRGLTFEAQDN	192
Monodelphis domestica	QVLRCVAQGTLESLLNSTQQLEATTEALDQAAGWAGGRRLTFETPGN	182
Gallus gallus	KVILCISKNSSESLLNSTDLLGNTFWKLEHELQ——NYLIWKPMDGHIQ	196
Alligator mississippiensis	QVIKCICKNSSESLLNSTALLGSASWEFGHHIKPVFDSLLVWKPMNGPFQ	193
Xenopus (Silurana) tropicalis	RTLGCLSQHSSERLLNSTFFFQTMTSDTNDIVT-EMKNLLSSKKSD—VK	179

CLUSTALW2 alignment of OC-STAMP sequences from representative taxa show complete conservation of the Asp residue in a glycosylation motif (bold, underlined) and its amino acid context. It is present in rodents (Mus musculus), ungulates (Bos taurus), giant panda (Ailuropoda melanoleuca), primates (Homo sapiens), marsupials (opossum; Monodelphis domestica), birds (Gallus gallus), amphibians (Xenopus (Siluriana) tropicalis), and reptiles (Alligator mississippiensis). Alignments were performed of the whole protein sequences and the number of the last amino acid shown is listed on the right. The GenBank sequences used for the alignments were: gi|21312818, gi|297482088, gi|301787077, gi|225637556, gi|126303342, gi|118100617, gi|564236812, and gi|301607266, respectively.