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The demonstration of Lipinski’s rule of 5 for the Analogs
| Name | Mol. wt. | No. of H-bond donors | No. of H-bond acceptors | logP | No. of flexible bonds | State based on ADME-Tox |
|---|---|---|---|---|---|---|
| Terbinafine | 301.36 | 1 | 5 | 3.5 | 5 | Accepted |
| Analog1 | 443.56 | 3 | 7 | 1.13 | 8 | Accepted |
| Analog2 | 400.53 | 3 | 5 | 4.65 | 7 | Accepted |
| Analog3 | 494.63 | 5 | 9 | 3.55 | 10 | Accepted |
