Video 9. Single-cell analysis of CtA formation in gpr124 mosaic animals. A single wild-type tip cell is sufficient to initiate the formation of an intra-cerebral CtA.
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DOI: 10.7554/eLife.06489.024
Time-lapse confocal video generated from maximum intensity confocal projections through one hindbrain hemisphere of a mosaic embryo containing wild-type kdrl:GFP+ ECs (green) and gpr124s984/s984 kdrl:ras-mCherry+ ECs (red). Video starts at 30 hpf and ends at approximately 40 hpf (anterior to the left).