Fig. 6.

a Comparative effects of native etoposide, CCNBs, and ECCNBs on p53-related signaling pathway in SGC-7901 cells by immunoblotting with specific antibodies mentioned in Materials and Methods. Effects of native etoposide, CCNBs, and ECCNBs on the expression of p53. b Western blot illustrating expression of apoptotic markers in SGC-7901 cells. Cells in culture were exposed to 30 μg/mL of native etoposide, CCNBs, and ECCNBs for indicated time periods. Effects of native etoposide, CCNBs and ECCNBs on the expression of caspase-7, caspase-8, caspase-9, and Cyt C