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. 2015 Jun 5;6:562. doi: 10.3389/fmicb.2015.00562

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Copyright © 2015 Beattie and Reyes-Lamothe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mechanism of replication termination in E. coli. (A) Schematic of the E. coli chromosome showing the approximate location of ter sites relative to oriC. Arrowheads indicate the permitted direction of replisome progression. Adapted from Duggin et al., 2008. (B) Mechanism of replisome trapping in the terminus region by Tus-ter. Just two ter sites are shown for clarity but the same mechanism can operate at any ter site. (C) Resolution of DNA structures following replisome convergence during termination.