Table 2. Numbers of Genes with Differential H3K27me3 in IM Compared to SAM and in SDG711 RNAi IM Compared to the Wild Type.
|
IM/SAM | |||
|---|---|---|---|
| H3K27me3 Loss | H3K27me3 Gain | Genome | |
| Total | 5,014 (191↑140↓) | 3,721 (122↑72↓) | 55,546 |
| Protein kinases | 168* (7↑5↓) | 155* (6↑2↓) | 1,600 |
| Transcription factors | 219* (17↑13↓) | 133* (9↑6↓) | 1,549 |
| SDG711 RNAi IM/wild type | |||
| K27me3 Loss |
H3K27me3 Gain |
Genome |
|
| Total | 5,406 (134↑65↓) | 1,378 (28↑16↓) | 55,546 |
| Protein kinases | 248* (4↑2↓) | 39 (0↑0↓) | 1,600 |
| Transcript factors | 120 (11↑4↓) | 36 (2↑0↓) | 1,549 |
Numbers of genes that showed upregulation (indicated by upwards arrows) or downregulation (indicated by downwards arrows) by more than 2-fold (P value < 0.05) are in parentheses. Significant enrichments (Fisher’s tests, P value < 0.05) are indicated by asterisks.