Skip to main content
. 2015 Jun 5;5:10903. doi: 10.1038/srep10903

Figure 2. Mitochondrial function in Gaucher fibroblasts is recovered by CoQ and PC NAdBT-AIJ treatments.

Figure 2

Control and Gaucher-B fibroblasts were cultured in the absence or presence of CoQ (25 μM), PC NAdBT-AIJ (25 μM) or CoQ + PC (25 μM + 25 μM) for 96 h. (a) Mitochondrial membrane potential (ΔΨm) in control and Gaucher fibroblasts. ΔΨm was assessed by flow cytometry using MitoTracker Red staining. (b) Adenosine-5’-triphosphate (ATP) levels in control and Gaucher fibroblasts. (c) Cell proliferation of control and Gaucher fibroblasts. For the control cells the data are the means±SD of three different control cell lines. Data represent the mean±SD of 3 separate experiments. *p < 0.01 between control and Gaucher fibroblasts. ap < 0.05 between the presence and the absence of CoQ. bp < 0.05 between the presence and the absence of PC. cp < 0.05 between the presence and the absence of CoQ+PC. #p < 0.05 between CoQ+PC and CoQ or PC treatment.