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Radiographs of type II collagen disorders. A. Achondrogenesis II in the late second trimester. Note the severe rhizo- and mesomelia with relative sparing of the hands, lack of ossification of the vertebral bodies and absent ischia. B. Hypochondrogenesis in the late second trimester. Vertebral bodies are under ossified with dumb-bell shaped humeri and femora, and lack of ossification of the ischia.
