Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Pain
RCT	348 children aged 12–17 years with moderate or severe headache pain (the intention-to-treat population consisted of 274 [80%] participants who completed treatment consistent with the study protocol)	Proportion of children with headache response (headache response was defined as improvement in headache pain intensity from moderate to severe at baseline to mild or no pain after treatment) 2 hours 80/141 (57%) with eletriptan 76/133 (57%) with placebo	P >0.05		Not significant