Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Migraine frequency
Systematic review	33 children aged 3–15 years with migraine (defined as episodic headaches impairing performance, plus at least 3 of: pulsating, frequently unilateral, vomiting, nausea, photophobia, visual impairment, and positive family history) Data from 1 RCT	Proportion of children with >75% improvement in headache frequency after 4 months of treatment 13/17 (76%) with flunarizine 12/15 (80%) with propranolol	OR 0.81 95% CI 0.15 to 4.40 Reported as not significant P value not reported		Not significant