Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	33 children aged 3–15 years with migraine (defined as episodic headaches impairing performance, plus at least 3 of: pulsating, frequently unilateral, vomiting, nausea, photophobia, visual impairment, and positive family history) Data from 1 RCT	Adverse effects 3/17 (18%) with flunarizine 5/15 (33%) with propranolol	Risk difference –0.16 95% CI –0.46 to +0.14 Reported as not significant P value not reported		Not significant