Table 1.
Adipokines | Serum levels in obesity | Effects on reproduction in obesity |
---|---|---|
Leptin | Increases (leptin resistance occurred in obesity) | Inhibits insulin induced ovarian steroidogenesis |
Inhibits LH*-stimulated estradiol production by the granulosa cells | ||
Adiponectin | Decreases | Plasma insulin levels increase |
Resistin | Increases | Causes insulin resistance |
Visfatin | Increases | Increased insulin sensitivity |
Omentin | Decreases | Increased insulin sensitivity |
Chemerin | Increases | Negatively regulates FSH§-induced follicular steroidogenesis |
luteinizing hormone
follicle stimulating hormone
FSH: follicle stimulating hormone; LH: luteinizing hormone