Figure 3. The anti-inflammatory effect of HMGB1 was canceled in the absence of PDGFRα⁺ mesenchymal cells.

a: The percentages of GFP⁺/PDGFRα⁺ cells recruited into skin grafts on PBS-administered total BMT mice, and PBS- or HMGB1-administered ckit⁺ BMT mice. b: Skin grafts stained by H&E. The boxed regions in the upper panels (×10, bar = 200 μm) are displayed at higher magnification (×40, bar = 50 μm) in the lower panels. (c): Representative images of skin grafts stained for CD68. Nuclei were stained with DAPI. Bar = 100 μm. (d): The number of CD68⁺ cells per field was quantified. e: The expressions of TNF-α, IL-1β, TSG-6, and IL-10 in skin grafts (n = 4–5). *P < 0.05.