Figure 2. L-citrulline protectd endothelial function from the impairment of ADMA in PCA.

Endothelium-dependent relaxation was partially restored by L-citrulline in arteries exposed to ADMA for 24 h. Endothelium-independent vasorelaxation to BK was affected by ADMA exposure and the differences were observed among groups treated with or without L-citrulline. Data are shown as mean ± SEM. (**p < 0.01, vs. control group. # p < 0.05, vs. ADMA group. n = 9, two-way ANOVA).