Figure 4.

The model of Ca²⁺-bound form of Syt1. (A) Two views (from opposite sides) of the C2B Ca²⁺-binding pocket. Residues forming coordination bonds are labeled. (B) Space filled model of Ca²⁺ ions chelated at the C2B Ca²⁺-binding pocket. (C) Schematic representation of Ca²⁺ coordination bonds at C2B domain. (D) Coordination bonds at C2B domain along the trajectory. The distances between Ca²⁺ ions and oxygen atoms are plotted, red arrows mark formed coordination bonds. (E–H) Ca²⁺ binding at the C2A domain (similar to A–D for C2B domain) is shown. To see this figure in color, go online.