. Author manuscript; available in PMC: 2015 Jun 5.

Published in final edited form as: Behav Brain Res. 2014 Jan 7;262:101–108. doi: 10.1016/j.bbr.2013.12.014

Table 1.

Novel open field activities exhibited by adolescent rats

Experimental Measure	Adolescent Locomotor Activity (cm/5 min)
	LLA		HLA
	Saline injected	Nicotine injected	Saline injected	Nicotine injected
CPP
Saline conditioned	5760 ± 154 (n=5)	5711 ± 189 (n=5)	6766 ± 292 (n=5)	6760 ± 275 (n=5)
Ethanol conditioned	5788 ± 233 (n=5)	5860 ± 167 (n=5)	6883 ± 139 (n=5)	6826 ± 251 (n=5)

Adolescent ΔFos B
4 days	5428 ± 106 (n=4)	5465 ± 82 (n=4)	6130 ± 179 (n=4)	6403 ± 341 (n=4)
8 days	5423 ± 176 (n=4)	5341 ± 230 (n=4)	6346 ± 251 (n=4)	6273 ± 250 (n=4)

Adult ΔFos B	5243 ± 354 (n=4)	5297 ± 356 (n=4)	6456 ± 156 (n=4)	6687 ± 230 (n=4)

Novel open field activity of animals used to assess the effect of adolescent nicotine exposure on ethanol conditioned place preference or ΔFosB expression in adolescence or adulthood. Following behavioral characterization on PND 31, animals were systematically assigned to experimental groups to ensure that baseline activity was equivalent for groups receiving injections of saline or nicotine. Values represent group means ± sem.