Figure 5.
Cells counts of HM01 induced c-Fos expression in the selective brain and spinal cord areas of 6-OHDA and control rats. Non-fasted rats treated with og administration of vehicle or HM01 (3 mg kg−1) were sacrificed 2 h later for immunohistochemical analysis. Positive neurons for c-Fos were counted in the arcuate nucleus (A), AP (B), NTS (C), and IML of lumbrosacral the spinal cord (D). Data are mean ± SEM of n = 3–4 rats per group. *P < 0.05 6-OHDA_Vehicle vs. Control_Vehicle; †P < 0.05 HM01 vs. each Vehicle. AP, area postrema; IML, intermediolateral column; NTS: nucleus of tractus solitarius.
