TABLE 5.
Studies of Ileal Pouch-Anal Anastomosis for Crohn’s Disease
| Diagnostic Criteria for Crohn’s Disease |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Study (yr) | N | Skip Lesion |
Granuloma | Perianal Disease |
Stricture | Transmural Inflammation |
Small Bowel Disease |
Postop CD (%) |
Pouch Failure (%) |
| Preop CD Diagnosis | |||||||||
| Hyman (91) | 9 | + | − | + | + | − | + | NS | 89 |
| Regimbeau (01) | 26 | + | All | − | − | − | − | 15 | NS |
| Melton (08) | 20 | − | All | − | − | + | − | NS | 15 |
| Shen (10) | 11 | Pre-rx | All | NCG | + | + | + | 64 | 9 |
| Grucela (11) | 13 | − | All | − | + | + | − | NS | 15 |
| Current study | 17 | Pre-rx | True | + | − | − | + | 41 | 6 |
| Postop CD Diagnosis | |||||||||
| Grobler (93) | 10 | NS | All | NS | NS | NS | NS | NS | 30 |
| Morpurgo (03) | 13 | − | All | + | − | + | − | 62 | 23 |
| De Oca (03) | 12 | + | All | − | − | + | − | 16 | 16 |
| Brown (05) | 36 | + | All | + | − | + | + | NS | 56 |
CD, Crohn’s disease; Pre-rx, pretreatment; NCG, noncryptoglandular; NS, not stated.