Table 3.
Entry | Compound | R | Yield (%) | IC50 (%) | I200 (%) |
---|---|---|---|---|---|
1 | 3a | 74 | >200 | 19 | |
2 | 3b | 25 | 50 | 78 | |
3 | 3c | 58 | >200 | 44 | |
4 | 3d | 95 | >200 | 48 | |
5 | 3e | 95 | >200 | 14 | |
6 | 3f | 66 | >200 | 25 | |
7 | 3g | 76 | >200 | 36 | |
8 | 3h | 57 | 40 | 81 | |
9 | 3i | 95 | >200 | 26 | |
10 | 3j | 97 | >200 | 87 |