Table I.
Baseline demographics
| Survivors n=84 | Controls n=98 | p | |
|---|---|---|---|
| Age (y), mean (95% CI) | 25.6 (24.3-27.0) | 26.9 (26.0-27.9) | 0.10 |
| BMI, mean (95% CI) | 24.1 (22.9-25.3) | 25.2 (24.0-26.5) | 0.21 |
| Race- Caucasian, % (n) | 92 (77/84) | 81 (79/98) | 0.03 |
| Education>College Graduate, % (n) | 55 (46/84) | 74 (70/98) | <0.007 |
| Marital status- single, % (n) | 67 (56/84) | 74 (70/98) | 0.10 |
| Living with partner, % (n) | 34 (30/84) | 24 (24/98) | 0.09 |
| Previous pregnancy, % (n) | 18 (15/84) | 27 (25/98) | 0.15 |
| Gravidity, mean (range) | 1.8 (1-3) | 1.7 (1-5) | |
| Parity, mean | 1.3 | 0.8 | |
| Reported time to pregnancy (months), mean | 3.7 | 0.8 | 0.30 |
| Report current contraceptive use, % (n) | 74 (62/84) | 64 (63/98) | 0.15 |
| Report contraceptive use with a hormonal method, % (n) | 32 (20/62) | 10 (6/63) | 0.02 |
| Menstrual Function, % (n) | 86 (73/84) | 100 (98/98) | <0.001 |
| Report regular menstrual cycles and are not using exogenous hormones, % (n) | 86 (56/65) | ||
| FSH mIU/mL, mean (95%CI)* | 13.9 (10.4-16.4) | 7.2 (6.6-8.0) | <0.001 |
| LH mIU/mL, mean (95% CI)* | 5.3 (4.3-7.2) | 3.8 (3.3-4.3) | 0.02 |
| Inhibin pg/mL, mean (95% CI)* | 27.0 (22.1-36.2) | 39.1 (32.5-47.4) | 0.03 |
| Estradiol pg/mL, mean (95% CI)* | 24.1 (21.5-29.8) | 25.4 (22.7-28.7) | 0.7 |
| AMH ng/mL, mean (95% CI)* | 0.7 (0.5-1.0) | 2.4 (2.0-2.7) | <0.001 |
| AFC, mean (95% CI)* | 11.3 (9.0-14.4) | 22.8 (20.3-26.0) | <0.001 |
| Ovarian volume cm3, mean (95% CI)* | 9.9 (8.9-13.4) | 14.3 (13.1-16.1) | 0.001 |
*
Geometric mean shown. Adjusted for age, race, and BMI.