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Transient response to abrupt changes in the pacing rate between 0.25 and 2 Hz. (A–H) Core IFM (black) and SSM (red) responses are compared using the same (equal model; A–D, upper panels) and different (hetero model; E–H, lower panels) enzymatic activities. From left to right: mitochondrial Ca2+, NADH, ADP, and inner membrane potential. In each panel, data averaged over the mitochondrion are shown. To see this figure in color, go online.
