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. 2012 Sep 28;70(13):2319–2329. doi: 10.1007/s00018-012-1171-6

Table 1.

Alternatively spliced Dab1 isoforms

Species Alternative splicing events Sequence difference relative to the canonical Dab1 Ref.
Chicken Exclusion of exons 7 and 8 and inclusion of exon 9b Deletion of 35 aa containing Y198, Y200 and Y220, insertion of 19 aa [31, 65]
Pig Exclusion of exons 7 and 8 and inclusion of exons 9b and 9c Deletion of 35 aa containing Y198, Y200 and Y220, insertion of 33 aa [71]
Lizard Inclusion of exon 9b Insertion of 19 aa [67]
Zebrafish Exclusion of exons 8 and 9 Deletion of 42 aa containing Y200, Y220 and Y232 [68]
Human Alternative promoter usage NA [67]
Human Exclusion of exons 7 and 8 and inclusion of exons 9b and 9c Deletion of 35 aa containing Y198, Y200 and Y220, insertion of 33 aa [70]
Mouse Exclusion of exon 7 Deletion of 13 aa containing Y198 [63]
Mouse Exclusion of exon 8 Deletion of 22 aa containing Y200 and Y220 [63]
Mouse Exclusion of exons 7 and 8 Deletion of 35 aa containingY198, Y200 and Y220 [63]
Mouse Inclusion of exons 9b and 9c Insertion of 33 aa [63, 66, 67, 69]
Mouse Exclusion of exons 7 and 8 and inclusion of exons 9b and 9c Deletion of 35 aa containing Y198, Y200 and Y220, insertion of 33 aa [63]
Mouse Exclusion of exon 8, inclusion of exons 9b and 9c Deletion of 22 aa containing Y200 and Y220, insertion of 33 aa [63]
Mouse Alternative 5′ splice site of intron 9 Deletion of 2 aa (valine and serine) [63]
Mouse Alternative 5′ splice site of intron 9, exclusion of exons 7 and 8 Deletion of 2 aa (valine and serine), deletion of 35 aa containing Y198, Y200 and Y220 [63]
Mouse Alternative 5′ splice site of intron 9, inclusion of exons 9b and 9c Deletion of 2 aa (valine and serine), insertion of 33 aa [63]
Mouse Alternative 5′ splice site of intron 9, exclusion of exons 7 and 8, inclusion of exons 9b and 9c Deletion of 2 aa (valine and serine), deletion of 35 aa containingY198, Y200 and Y220, insertion of 33 aa [63]
Mouse Alternative 5′ splice site of intron 9, exclusion of exons 7 and 8 Deletion of 2 aa (valine and serine), deletion of 35 aa containingY198, Y200 and Y220 [63]
Mouse Alternative 5′ splice site of intron 9, inclusion of exons 9b and 9c Deletion of 2 aa (valine and serine), insertion of 33 aa [63]
Mouse Alternative 5′ splice site of intron 9, exclusion of exons 7 and 8, inclusion of exons 9b and 9c Deletion of 2 aa (valine and serine), deletion of 35 aa containing Y198, Y200 and Y220 and insertion of 33 aa [63]
Mouse Inclusion of exon 7a Addition of 18 aa with a stop codon [69]
Mouse Inclusion of exon 9a Addition of 31 aa with a stop codon [69]