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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Biomaterials. 2015 Jan 22;47:1–12. doi: 10.1016/j.biomaterials.2014.12.043

Figure 3. Dependency of cell proliferation on hydrogel stiffness and adhesion peptide density.

Figure 3

a, RSM plots of CPC proliferation in HyA-PHT hydrogels with various moduli and concentrations (120–380 μM) of the cell adhesive ligand bsp-RGD (15). CPC proliferation was dose-dependent on the RGD density, and maximum at ~ 800 Pa. All data was normalized to the cell number (3.48×105) in hydrogels at day 3 data. b, Kinetic observations of CPC proliferation as a function of hydrogel stiffness in HyA-PHT hydrogels shown at three different bsp-RGD(15) densities.