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. Author manuscript; available in PMC: 2016 Jun 21.
Published in final edited form as: Lab Chip. 2015 Jun 21;15(12):2625–2633. doi: 10.1039/c5lc00245a

Figure 3.

Figure 3

Neutrophil migration patterns change in the presence of zymosan particles. (A) Migration tracks for two neutrophils towards 100 nM LTB4 (no zymosan). Chemotaxis (upward-pointing black arrow) is followed by retrotaxis (downward-pointing blue arrow) towards the central whole-blood loading chamber. (B) Migration tracks for two neutrophils towards 100 nM LTB4-zymosan filled (bright green particles) CC. Red circles represent the end of the migration trajectory due to phagocytosis. Trafficking profiles of recruited neutrophils to zymosan-free CCs (C) and zymosan-filled CCs (D). “Enter” profiles represent the entry times to the CC of chemotaxing neutrophils, “Exit” profiles represent the exit time from the CC of retrotaxing neutrophils, and “Trapped” represent the difference between the “Enter” and “Exit” profiles. “Exit” trajectory decreases significantly when compared to the control zymosan-free control condition.