Table 1.
Demographic, exposure, and clinical characteristics of cases and controls
| Cases N=256 |
Controls N=250 |
p | |
|---|---|---|---|
| Age, mean (SD) | 56.5 (9.6) | 56.5 (9.6) | .963 |
| Age, median | 55 | 55.5 | .930 |
| N (%) | N (%) | ||
| Sex | .913 | ||
| Male | 220 (85.9) | 214 (85.6) | |
| Female | 36 (14.1) | 36 (14.4) | |
| Race | .691 | ||
| White | 233 (91.0) | 230 (92.0) | |
| Other | 23 (9.0) | 20 (8.0) | |
| Alcohol | <.001 | ||
| Never | 71 (27.7) | 111 (44.4) | |
| Former | 66 (25.8) | 47 (18.8) | |
| Current | 119 (46.5) | 92 (36.8) | |
| Smoking | .007 | ||
| Never | 116 (45.3) | 131 (52.4) | |
| Former | 93 (36.3) | 97 (38.8) | |
| Current | 47 (18.4) | 22 (8.8) | |
| Smokinga | |||
| ≤10 pack years | 149 (59.6) | ||
| >10 pack years | 101 (40.4) | ||
| HPV statusb | |||
| Negative | 26 (19.0) | ||
| Positive | 111 (81.0) | ||
| Subsite | |||
| Tonsil | 122 (47.7) | ||
| Base of tongue | 121 (47.3) | ||
| Other oropharynx | 9 (3.5) | ||
| Other site (not oropharynx) | 4 (1.6) | ||
| Stage | |||
| I–II | 19 (7.4) | ||
| III–IV | 237 (92.6) | ||
| T category | |||
| 0–1 | 76 (29.7) | ||
| 2 | 110 (43.0) | ||
| 3 | 41 (16.0) | ||
| 4 | 29 (11.3) | ||
| N category | |||
| 0 | 29 (11.3) | ||
| 1–2a | 42 (16.4) | ||
| 2b | 126 (49.2) | ||
| 2c-3 | 59 (23.1) | ||
| Gradec | |||
| Well to moderate | 76 (34.5) | ||
| Moderately Poor to poor | 144 (65.5) | ||
a
Total N=250 cases due to missing data (N=6)
b
Total N=137 cases due to missing data (N=119)
c
Total N=220 cases due to missing data (N=36)