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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Neurobiol Aging. 2015 Mar 25;36(7):2241–2247. doi: 10.1016/j.neurobiolaging.2015.03.011

Figure 2. Murine Aβ is part of Aβ plaques of APP23 and APPPS1 mice.

Figure 2

Immunohistological staining for murine Aβ (m3.2 antibody) revealed its localization in Aβ plaques of 14.5 month-old APP23 (A) and 3 month-old APPPS1 (B) mice. Plaques were counter-stained with the amyloid-specific fluorescent dye pFTAA. As expected, no staining of murine Aβ was observed in koAPP23 and koAPPPS1 mice. Two representative animals were examined for each group (4 brain sections/animal). Scale bar is 20 μm for (A) and 10 μm for (B). Images in (B) represent maximum intensity projections of six z-planes each.