Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ex vivo PIB binding in APPPS1, koAPPPS1 and human AD sample
| Sample | Total cpm | + 1 μm PIB | Difference | % Specific Binding |
|---|---|---|---|---|
| AD brain | 8517 ± 191 | 1329 ± 32 | 7188 | 84.4 |
| APPPS1 | 3893 ± 2.1 | 1383 ± 77 | 2510 | 64.5 |
| koAPPPS1 | 3610 ± 398 | 1401 ± 42 | 2209 | 61.2 |
The binding efficiency of the PET tracer PIB was measured in brain samples from an AD patient and 8.5-9.5 month-old APPPS1 and koAPPPS1 mice. Results for AD brain and APPPS1 mice are in line with previous findings (Klunk et al., 2005).
