. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Genes Immun. 2015 Mar 26;16(4):268–274. doi: 10.1038/gene.2015.7

Table 3.

Thyroiditis and autoantibodies to thyroglobulin (Tg) and thyroid peroxidase (TPO) enhanced by dietary iodide in mice on the NOD background differing at the MHC locus.

Strain	H2-K	I-A	I-E	H2-D	M/F	Thyroiditis	TgAb	TPOAb	Ref
NOD	d	g7	ne	b		minimal			(18;19)
	d	g7	ne	b	M	increased	no		(5)
NOD-E	d	g7	I-Eα^d ^*	b	M	increased	no		(5)
NOD-A-Asp	d	g7m	d	b	M	increased	no		(5)
NOD.H2^h4	k	k	ne	b		increased			(18;19)
	k	k	ne	b	M,F	increased	TgAb		(3–5;14)
	k	k	ne	b	M,F	increased	TgAb	TPOAb	(6)
	k	k	ne	b	M	increased	TgAb	TPOAb	Present study
NOD.H2^k	k	k	k	k	M	increased	TgAb	No TPOAb	Present study

ne, I-E not expressed;

I-Eβ expressed endogenously; g7m: I-A beta chain mutated to express Asp instead of Pro at position 57 (36); blanks indicate no information