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. Author manuscript; available in PMC: 2015 Dec 4.
Published in final edited form as: Nature. 2015 Apr 6;522(7554):94–97. doi: 10.1038/nature14306

Extended Data Fig. 6. Late and partial mesenchymal DP removal does not affect hair follicle regression.

Extended Data Fig. 6

a) Sequential revisits of hair follicles after DP-ablation during late regression. b) Box plot quantification of hair follicle length immediately following ablation, 4 days, and 11 days after DP-ablation (n = 20 follicles, in 4 mice; error bars represent max and min). c) Sequential revisits of hair follicles after partial DP-ablation during early regression (n = 12 follicles, in 3 mice). d) Schematic illustration of the results from mesenchymal DP-ablation experiments. DP-ablation during early regression results in failed elimination of the basal epithelium, while the inner layers continue upward in terminal differentiation, yet DP-ablation during late regression does not impair hair follicle regression. Asterisk indicates auto-fluorescence from the two-photon laser. Scale bars, 25 μm.