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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Mol Endocrinol. 2015 May 5;54(3):R151–R167. doi: 10.1530/JME-14-0308

Figure 2. A schematic of the cellular processes in which different polyubiquitin chain species have been implicated based on linkage type.

Figure 2

The different types of ubiquitylated species are represented as cartoons in the left-hand column. Polyubiquitin chains can be organized into a “closed” or “open” conformation based solely on the type of linkage that connects them. A (*) symbolizes that structural data is currently unavailable for these linkages; however, modeling of these structures predicts the conformation of each chain type. Cellular roles are determined based on the identification of each chain type in a specific cellular process. Currently the function of many of these chains is still unknown. This list is not meant to be comprehensive but rather to highlight the many diverse roles of ubiquitin.