Table 3.
Percent change in serum hormone concentration associated with a doubling (100% increase) in urinary organophosphate insecticide metabolite concentration in men aged 20–55 years from NHANES 1999–2002 (n=356)
| Biomarker | T [% change (95% CI)]
|
E2 [% change (95% CI)]
|
||
|---|---|---|---|---|
| Unadjusted | Adjusteda | Unadjusted | Adjusteda | |
| DEP | −2.4 (−3.7, −1.2)** | −2.5 (−3.5, −1.4)** | 0.1 (−1.4, 1.7) | −0.2 (−1.7, 1.4) |
| DETP | 0.4 (−3.6, 4.6) | 1.3 (−2.0, 4.6) | 1.3 (−3.5, 6.3) | 1.4 (−3.2, 6.2) |
| DMTP | −0.1 (−0.2, 0.1) | −0.02 (−0.2, 0.1) | −0.1 (−0.3, 0.1) | −0.1 (−0.3, 0.1) |
| TCPY | 0.2 (−1.4, 1.9) | 0.3 (−1.1, 1.7) | 1.8 (−0.2, 3.8)* | 1.5 (−0.5, 3.5) |
Abbreviations: CI, confidence interval.
a
Models were adjusted for age (continuous), BMI (continuous), serum cotinine concentration (continuous), urinary creatinine concentration (continuous), serum SHBG concentration (continuous), race/ethnicity (categorical), and education (categorical).
*
0.05 ≤p <0.10.
**
p <0.05.