Figure 8. NRPS-independent siderophore (NIS) synthetase inhibitor.
A. Condensation of citric acid (blue) with diaminopropionic acid (red) by NIS synthetase SbnE from S. aureus for the production of staphyloferrin. B. Condensation of citric acid (blue) with spermidine (green) by NIS synthetase AsbA from B. anthrasis for the production of petrobactin. C. Micromolar antibiotic inhibitor of SbnE and AsbA [61].