Skip to main content
. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2015 Apr 4;84:196–205. doi: 10.1016/j.freeradbiomed.2015.03.036

Figure 6. Ad-SOCS-1 administration reduces inflammatory cytokines in BAL in mice exposed to hyperoxia.

Figure 6

Male and female C57Bl/6 mice transfected with recombinant Ad-SOCS-1 and Ad-GFP were exposed to room air (Normoxia) or 100% O2 (Hyperoxia) at 72 h as described in Material and Methods. Proinflammatory cytokine levels (A) IL-1β, (B) IL-6, (C) TNF-α and (D) MCP-1 of SOCS-1- and GFP-treated mice under normoxic and hyperoxic conditions were analyzed using ELISA. **P < 0.01 when compared between Ad-GFP- and Ad-SOCS-1-transfected mice under hyperoxia.